Nature has afforded us 22 naturally occurring coded amino acids commonly found in proteins isolated from eukaryotic and prokaryotic sources. A variety of synthetic means have also been established to produce a great amount of non-proteinogenic amino acids as tools to investigate enzymatic mechanisms, extend biological half-life, establish a specific conformational determinant or increase potency of therapeutically interesting peptides. From these non-proteinogenic amino acid cyclopentylglycine shows great interest as a structural alternative to the natural aminoacids. Cyclopentylglycine is known as a competitive inhibitor of isoleucine uptake in E. coli 8 and has been used in designing angiotensin II antagonists. Due to this interest, Synthelia has included in its catalog three new derivatives of the S-cyclopentylglycine enantiomerically pure; The N boc protected methyl ester (CAS: 196206-09-4), methyl ester HCl ester (CAS: 14328-62-2), and the L-cyclopentylglycine (CAS: 2521-84-8) are the new three Synthelia compounds. The materials are provided from 5 g to bulk amount.
For more information: Synthelia Catalogue