Catalogue 2019-2020

In addition to the chemistry services and the on-demand synthesis supplied by Synthelia, you can find our company to be a reliable partner in providing chemicals to the industry: pharmaceutical companies, individual professionals, life sciences, educational institutes, pilot plants and laboratories, among others. We offer a very attractive compound collection, whose synthesis have been developed and optimized in our facilities to afford the highest quality and reproducibility of the batches, ranging from small to bulk scale.

The major concern for the company is the quality of the compounds that we offer. Thus, getting the highest level of quality starts with the selection process of the well-recognized suppliers for our raw materials. The manufacturing process is closely followed by the Quality Control Laboratory. A Certificate of Analysis accompanies an individual product during transport and an additional copy will be sent to the clients by e-mail.

Please do not hesitate to contact us with new product suggestions.

2019-2020 Catalogue

Download and check our catalogue

The catalogue is a downloadable file where you can find compounds with a wide range of functionalities such as pyrrolidones, phenylacetic acids, benzoic acids, phenols, amino alcohols, indoles, pyrazoles, oxazoles, 4-quinolinols (explained in detail in the next section), etc.

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New Synthelia ́s Launches…

4-QUINOLINOL OR 4-QUINOLONE? That’s the question

 At Synthelia Organics, we consider that 4-quinolinol core and its derivatives represent an important building block group in construction and development of new pharmaceuticals. This core is present in several commercially available drugs and in others with promising perspectives.

For this reason, Synthelia has set up an in-house program to design and produce diverse 4-quinolinols that can be used both as building blocks and for SAR studies in organic synthesis and medicinal chemistry. As the result of the program, Synthelia is pleased to introduce the new catalog dedicated to the 4-quinolinol derivatives.

 At Synthelia Organics, we consider that 4-quinolinol core and its derivatives represent an important building block group in construction and development of new pharmaceuticals. This core is present in several commercially available drugs and in others with promising perspectives.

For this reason, Synthelia has set up an in-house program to design and produce diverse 4-quinolinols that can be used both as building blocks and for SAR studies in organic synthesis and medicinal chemistry. As the result of the program, Synthelia is pleased to introduce the new catalog dedicated to the 4-quinolinol derivatives.

And of course the whole “floxacines” family, with a wide antibiotic activity.

Synthelia has developed a large variety of products within the 4-quinolinol family offering pharmaceutical companies a wide range of possibilities to carry out SAR studies. Functionalization at different positions and with different functional groups expands possibilities to use 4-quinolinol as a scaffold.

Most of the compounds are available in a short delivery time even at large scale and at competitive prices. The following list is not exhaustive and if you do not find what you are looking for, we welcome inquiries for products not specifically listed in the catalog. Please do not hesitate to contact us with new product suggestions.

As an example of the possibilities that 4-quinolinoles offer, we have prepared brief descriptions of some drugs that contains this scaffold:

 BOSUTINIB (Wyeth/Pfizer), approved for treatment of adult patients with Ph+ chronic myelogenous leukemia (CML) with resistance or intolerance to prior therapy and it is now being tested for use in cancer treatment.

 ELVITEGRAVIR (Gilead Sciences) is an integrase inhibitor used to treat HIV infection.

 GALUNISERTIB (Eli Lilly and co.) a potent TGFβ receptor I (TβRI) inhibitor currently in phase II/III trials for several cancer (colorectal carcinoma, myelodysplastic syndromes, and many others).