DRUG DISCOVERY & MEDICINAL CHEMISTRY
Synthelia is specialist in Custom Synthesis, providing you with support during your Medicinal Chemistry processes:
- Synthesis of standards with high purity for biological models.
- Support in the synthesis of compounds to speed up the SAR.
- Close monitoring of the project to identify possible common key intermediates.
- Rapid scale up to deliver the product needed for preclinical assays.

Collaborative models:
To meet clients’ needs for custom synthesis, we suggest an FTE (full-time employee) collaboration at our facilities.
Our facilities include:



More than 500 m² dedicated to R&D
15 Fume hoods
Carousels for parallel synthesis



H-Cube® reactor
Ozone generator
Biotage automated chromatography system for purification



Preparative HPLC
0.5 L pressure vessel
Full access to SciFinder® database
PRECLINICAL DEVELOPMENT AND CLINICAL SUPPLY

Move your project from medicinal chemistry to process chemistry with the aid of Synthelia:
- Design, evaluation, and development of novel synthetic routes.
- Efficiently, green, and safely route scouting during transfer to pilot plant.
- Scale up of lead compounds to support toxicity assays.
- Synthesis of Registered Starting Materials (RSM) for APIs preparation.
- Integral transfer of technology and knowledge to the client.
- As manufacturers of RSM, we comply with the quality standards of our clients according to their audits.
To support all these activities, we have a Quality Department in charge of developing all the documentation you may need for the validation of your process, assuring compliance with specifications under a GMP perspective.
Our Facilities with the following capabilities are:



More than 200 m² dedicated to production in two separate pilot plants
More than 100 m² of laboratory with 4 walking fume hoods
Total reactor volume 1 m³



Stainless steel reactors up to 200 L
5 L Pressure reactor up to 60 bar
Operational temperature ranges: -90 °C to 250 °C


